| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Moore, Alexandra G (12)
|
CTCPAC |
4:49.03 |
4:40.24 |
-8.79 |
| 2 |
Lazar, Penelope A (12)
|
CTGYWD |
4:45.09 |
4:42.39 |
-2.70 |
| 3 |
Racanello, Briana (12)
|
MRLIAC |
4:47.37 |
4:43.70 |
-3.67 |
| 4 |
Lam, Makani S (11)
|
MRLIAC |
4:49.24 |
4:50.18 |
0.94 |
| 5 |
Armstrong, Brooke E (12)
|
MRLIAC |
5:38.77 |
4:51.75 |
-47.02 |
| 6 |
Crouchley, Caroline A (12)
|
MRLIAC |
5:13.18 |
4:53.48 |
-19.70 |
| 7 |
Han, Abigail N (12)
|
MRLIAC |
5:07.64 |
4:58.12 |
-9.52 |
| 8 |
Carter, Madisyn (12)
|
PVNCAP |
5:10.46 |
5:05.26 |
-5.20 |
| 9 |
Dunn, Zoe E (12)
|
PVNCAP |
5:10.43 |
5:09.04 |
-1.39 |
| 10 |
Lee, Makayla (12)
|
MRSSC |
5:18.99 |
5:10.74 |
-8.25 |
| 11 |
Caraballo, Isabella K (12)
|
MAWAC |
5:18.79 |
5:11.99 |
-6.80 |
| 12 |
Sanchez, Erin V (12)
|
PVMACH |
5:29.84 |
5:23.75 |
-6.09 |
| 13 |
Kellner, Gabriella H (11)
|
MACBST |
5:29.63 |
5:27.88 |
-1.75 |
| 14 |
Cypher, Ella M (11)
|
PVNCAP |
5:27.87 |
5:30.81 |
2.94 |